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Does green tea fight cancer?

In December 2005, the Mayo Clinic in Rochester, Minn., released a case study suggesting green tea improved the conditions of four people with chronic lymphocytic leukemia.

The four patients consumed over-the-counter products containing epigallocatechin-3-gallate (EGCG), the active ingredient in green tea. Hematologist Tait Shanafelt, M.D., and colleagues tracked the patients' conditions, and preliminary evidence suggested positive clinical effects. The findings appeared in the journal Leukemia Research.

Green Tea: Miracle Cure?
The Chinese have consumed green tea for some 5,000 years. It contains antioxidants called flavonoids - also found in leafy vegetables - which are thought to prevent cancer.

Green tea has been used to treat hypertension and atherosclerosis. Studies have shown EGCG to modulate the growth factor leading to leukemic cells, while theaflavin-enriched green tea extract has been shown to lower cholesterol and may reduce the risk of hypertension.

Researchers such as Thomas Gasiewicz, Ph.D., chair of the Department of Environmental Medicine at the University of Rochester (UR) in New York, have studied green tea's chemopreventive abilities.

In 2003, Gasiewicz and his colleagues at UR 's Environmental Health Sciences Center determined that chemicals in green tea shut down the aryl hydrocarbon (AH) receptor, one of the key molecules in tobacco that may spur cancer.

Chemicals in green tea successfully shut down the AH receptor in cancerous cells in mice. The manner in which green tea is metabolized in the human body is still not fully understood, so more research is needed, according to Gasiewicz.

"The data from studies on human populations are not convincing as to a health benefit of green tea consumption," Gasiewicz said. "Some studies show some benefit; some studies do not. However, the evidence from animal investigations is more convincing for an anti-cancer activity of green tea and its components."

"Determining how these chemicals work in animals may help us to understand how they might - or might not - act in humans and the concentrations that may be effective. This information may also assist in the design of agents that may be more effective in humans for anti-cancer therapy," he said.

The Mayo Clinic research team also stated that more studies are needed to determine optimal doses, side effects and the frequency of medication before green tea can be recommended for widespread use among cancer patients.


FDA Weighs In
The U.S. Food and Drug Administration (FDA) says there's no concrete scientific evidence to support claims that green tea prevents cancer.

In a June 2005 statement, the FDA cited studies with conflicting information about the effectiveness of green tea in preventing certain types of cancer. While two studies revealed that green tea didn't demonstrably reduce the risk of breast cancer, one "limited" study suggested that it might. Similarly, while one study found that green tea didn't reduce the risk of prostate cancer, a smaller study found that it did.

As part of the FDA's Consumer Health for Better Nutrition Initiative, experts concluded that it is highly unlikely that green tea reduces the risk of breast cancer and prostate cancer. The FDA also concluded that qualified health claims for green tea consumption as a preventive measure for reducing the risk of other types of cancers must be investigated further, as no substantial scientific evidence exists for such claims.


Should You Go Green?

Bradly P. Jacobs, M.D., M.P.H., chair of the Complementary and Alternative Medicine Channel for myDNA.com's Medical Advisory Board (MAB) said people who drink green tea tend to be more health-conscious, which could account for their lower cancer risk.

"Studies in Asia show that cancer is lower among those drinking green tea," he said. But "this could be a lifestyle issue."

Green tea may not prevent cancer, but it does have plenty of proven health benefits.

"Studies have shown that green tea - either oral or topical - has significant antioxidant, anti-inflammatory and anti-aging benefits," said Lisa Zanetti Rhodes, M.D., co-chair of the Skin Disorders Channel for myDNA.com's MAB.

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Green Tea Benefits Trivia:

Did you know that:

  • EGCG or epigallocatechin gallate is the most abundant antioxidant catechin in green tea. It is found in high amounts in this beverage as the green tea leaves undergo very minimal amounts of oxidation. EGCG in green tea has exceptional anti-inflammatory and immune strengthening properties. Read more about EGCG here.

  • Green tea is often classified as one of the so-called 'superfoods' due to its wealth of health-boosting components that may help fight a wide array of ailments and diseases. 'Superfood' is the term used to describe foods with high antioxidant and phytonutrient content. Go here to find a list of 'superfoods'.

  • Vitamin C is said to help the body absorb more of the antioxidant content of green tea. New studies have shown that taking citrus juices, like those of oranges and lemons, along with green tea enable more of the tea's antioxidants to remain after the digestion process is completed. Read more about Vitamin C here.

  • Antioxidants in green tea help fight the ravages of free radicals that are seen as the source of many of today's debilitating diseases. Did you know that aside from the catechins that are so abundant in green tea, there are many other types of antioxidants? Discover them all here.

  • Green tea is said to help in lowering calories and fighting fat. This seeming ability to aid in weight loss is attributed to the polyphenols found in the beverage. Read more about green tea's fat-fighting abilities here.

  • The Japanese and the people from the Meditteranean have some of the world's longest life expectancy rates. And while the Japanese look to green tea as their favorite after-meal drink, the Mediterranean peoples love to have red wine after their meals. Green tea and red wine? Could any two beverages be any more different? Discover what makes red wine a healthy drink when taken in moderation here.

  • The quality of the water used to brew the tea is very important. It is believed that the water used must be free of contaminants and contain enough oxygen to enhance the natural flavor of the tea. Teas made with pure water yield a crisp flavor and a clear brew that is aesthetically pleasant. Learn more about the health benefits of water here.


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